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Identification of common genetic polymorphisms associated with down-regulated gonadotropin levels in an exome-wide association study.

Fertility and sterility - 1 Sept 2023

Shi Yue, Miao Ben-Yu, Ai Xi-Xiong, Cao Ping, Gao Jun, Xu Yan, Yang Qun, Fei Jia, Zhang Qian, Mai Qing-Yun, Wen Yang-Xing, Qu Yan-Lin, Zhou Can-Quan, Xu Yan-Wen

Abstract excerpt

OBJECTIVE: To investigate whether common genetic polymorphisms are associated with gonadotropin levels after down-regulation with daily gonadotropin-releasing hormone agonist and whether the polymorphisms of candidate variants influence the ovarian response to exogenous gonadotropins. DESIGN: Genetic association study. SETTING: University-affiliated in vitro fertilization center. PATIENTS: Subjects enrolled in an...

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PMID: 37001689
DOI: 10.1016/j.fertnstert.2023.03.031

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