Article
DNA methylation and demethylation shape sexual differentiation of neurochemical phenotype.
Hormones and behavior - 1 May 2023
Cortes L R, Forger N G
Abstract excerpt
Some of the best-studied neural sex differences depend on differential cell death in males and females, but other sex differences persist even if cell death is prevented. These include sex differences in neurochemical phenotype (i.e., stable patterns of gene expression). Work in our laboratory over the last several years has tested the hypothesis that sex differences in DNA methylation early in life underlie...
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