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Effects of metabolic memory on inflammation and fibrosis associated with diabetic kidney disease: an epigenetic perspective

21 Apr 2021

Abstract excerpt

Diabetic kidney disease (DKD) is one of the most common microvascular complication of both type 1 (T1DM) and type 2 diabetes mellitus (T2DM), and the leading cause of end-stage renal disease (ESRD) worldwide. Persistent inflammation and subsequent chronic fibrosis are major causes of loss of renal function, which is associated with the progression of DKD to ESRD. In fact, DKD progression is affected by a...

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PMID: 33883002
DOI: 10.1186/s13148-021-01079-5

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