Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

B7H4 Expression Is More Frequent in MSS Status Colorectal Cancer and Is Negatively Associated with Tumour Infiltrating Lymphocytes

10 Mar 2023

Abstract excerpt

The immunotherapies based on ICIs in CRC are nowadays limited to microsatellite unstable tumours which are approximately 15% of all CRC cases. There are a few new immune checkpoints belonging to the B7 family, including B7H4. B7H4 expression is associated with so-called "cold tumours", and its function is linked to the downregulation of various immune cell populations. Our study aimed to investigate whether B7H4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Colorectal and Anal Carcinomas
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36980202
DOI: 10.3390/cells12060861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

B7H4 Expression Is More Frequent in MSS Status Colorectal Cancer and Is Negatively Associated with Tumour Infiltrating LymphocytesPMID 36980202Read ↗

Relationship between microsatellite status and immune microenvironment of colorectal cancer and its application to diagnosis and treatmentSemantic proximity Read ↗

sB7-H4 is a diagnostic biomarker in epithelial ovarian cancer and correlates to platinum resistanceSemantic proximity Read ↗

The Inhibitory Role of B7-H4 in Antitumor Immunity: Association with Cancer Progression and SurvivalSemantic proximity Read ↗

Decreased m6A Modification of CD34/CD276(B7-H3) Leads to Immune Escape in Colon CancerSemantic proximity Read ↗

The clinical and immune features of CD14 in colorectal cancer identified via large-scale analysis.Semantic proximity Read ↗

MAP7D2 reduces CD8+ cytotoxic T lymphocyte infiltration through MYH9-HMGB1 axis in colorectal cancerSemantic proximity Read ↗

To kill a cancer: Targeting the immune inhibitory checkpoint molecule, B7-H3Semantic proximity Read ↗

Mapk14 is a Prognostic Biomarker and Correlates with the Clinicopathological Features and Immune Infiltration of Colorectal CancerSemantic proximity Read ↗

Epigenetic-related gene mutations serve as potential biomarkers for immune checkpoint inhibitors in microsatellite-stable colorectal cancer.Semantic proximity Read ↗

Multi-omic analysis of colorectal adenocarcinoma identifies a new subtype of myofibroblastic cancer-associated fibroblast expressing high level of B7-H3 and with poor prognosis valueSemantic proximity Read ↗

Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal CancerSemantic proximity Read ↗

Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.