Rhnull phenotype: molecular basis, serologic features, clinical manifestations, and transfusion challenges-a scoping review of published cases.

Abstract excerpt

The Rhnull phenotype is the rarest of the Rh blood group system phenotypes and is characterized by the complete absence of all Rh antigens on red blood cells (RBCs). This phenotype carries major clinical relevance because of chronic hemolysis and profound transfusion incompatibility. We performed a scoping review to summarize the molecular basis, serologic features, clinical manifestations, and transfusion...

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