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Differentiation-related genes in tumor-associated macrophages as potential prognostic biomarkers in non-small cell lung cancer

8 Mar 2023

Abstract excerpt

Background The purpose of this study was to evaluate the role of differentiation-related genes (DRGs) in tumor-associated macrophages (TAMs) in non-small cell lung cancer (NSCLC). Methods Single cell RNA-seq (scRNA-seq) data from GEO and bulk RNA-seq data from TCGA were analyzed to identify DRGs using trajectory method. Functional gene analysis was carried out by GO/KEGG enrichment analysis. The mRNA and protein...

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PMID: 36969247
DOI: 10.3389/fimmu.2023.1123840

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