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Article

Immune response and drug therapy based on ac4C-modified gene in pancreatic cancer typing

6 Mar 2023

Abstract excerpt

N-4 cytidine acetylation (ac4C) is an epitranscriptome modification catalyzed by N-acetyltransferase 10 (NAT10) and is essential for cellular mRNA stability, rRNA biosynthesis, cell proliferation, and epithelial-mesenchymal transition (EMT). Numerous studies have confirmed the inextricable link between NAT10 and the clinical characteristics of malignancies. It is unclear, however, how NAT10 might affect...

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PMID: 36949954
DOI: 10.3389/fimmu.2023.1133166

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