Article
Single nucleotide variants in the IL33 and IL1RL1 (ST2) genes are associated with periodontitis and with Aggregatibacter actinomycetemcomitans in the dental plaque biofilm: A putative role in understanding the host immune response in periodontitis.
PloS one - 1 Jan 2023
Trindade Soraya C, Lopes Mabel P P, Oliveira Tatiane T M C, Silva Milca J, Queiroz Gerson A, Jesus Talita S, Santos Ellen K N, Carvalho-Filho Paulo C, Falcão Michelle M L, Miranda Patrícia M, Santos Rebeca P B, Figueiredo Camila A, Cruz Álvaro A, Seymour Gregory J, Gomes-Filho Isaac S
Abstract excerpt
The Interleukin (IL)-33 is important in several inflammatory diseases and its cellular receptor is the Interleukin 1 receptor-like 1 (IL1RL1), also called suppression of tumorigenicity 2 ligand (ST2L). This study investigated associations between single nucleotide variants (SNVs) in the IL33 gene and in the IL1RL1 (ST2) gene with periodontitis. Additionally, aimed to determine the role of Aggregatibacter...
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