Article
Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins
15 Dec 2011
Abstract excerpt
Keratins (Ks) consist of central α-helical rod domains that are flanked by non-α-helical head and tail domains. The cellular abundance of keratins, coupled with their selective cell expression patterns, suggests that they diversified to fulfill tissue-specific functions although the primary structure differences between them have not been comprehensively compared. We analyzed keratin sequences from many species:...
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