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Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair

10 Nov 2008

Abstract excerpt

The appearance of hair is one of the main evolutionary innovations in the amniote lineage leading to mammals. The main components of mammalian hair are cysteine-rich type I and type II keratins, also known as hard alpha-keratins or "hair keratins." To determine the evolutionary history of these important structural proteins, we compared the genomic loci of the human hair keratin genes with the homologous loci of...

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PMID: 19001262
DOI: 10.1073/pnas.0805154105

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