Article
Swimming against ALS: How to model disease in zebrafish for pathophysiological and behavioral studies.
Neuroscience and biobehavioral reviews - 1 May 2023
Oliveira Nuno A S, Pinho Brígida R, Oliveira Jorge M A
Abstract excerpt
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that leads to progressive disability and motor impairment. Existing therapies provide modest improvements in patient survival, raising a need for new treatments for ALS. Zebrafish is a promising model animal for translational and fundamental research in ALS - it is an experimentally tractable vertebrate, with high homology to humans and an ample...
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