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Article

Acquired crizotinib-resistant pulmonary adenocarcinoma and subsequent primary gallbladder cancer: A case report.

Medicine - 17 Mar 2023

Zhang Min, Chen Ruilin, Zheng Suqun, Wang Zhen

Abstract excerpt

RATIONALE: Proto-oncogene-oriented targeted therapy has limited benefits in elderly patients with multiple primary tumors. PATIENT CONCERNS: A woman with anaplastic lymphoma kinase-positive lung adenocarcinoma developed acquired resistance after 3 years of targeted therapy with crizotinib. DIAGNOSES: Diagnosis of unexpected subsequent primary gallbladder tumor. INTERVENTIONS: Lenvatinib was administered...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36930086
DOI: 10.1097/MD.0000000000033162
PMCID: PMC10019204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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