Article
PTEN mutation predicts unfavorable fertility preserving treatment outcome in the young patients with endometrioid endometrial cancer and atypical hyperplasia.
Journal of gynecologic oncology - 1 Jul 2023
Xue Yu, Dong Youting, Lou Yaochen, Lv Qiaoying, Shan Weiwei, Wang Chao, Chen Xiaojun
Abstract excerpt
OBJECTIVE: This study aimed to investigate the impact of molecular classification and PTEN, KRAS and PIK3CA gene mutation on the outcome of fertility-preserving treatment in the patients with endometrioid endometrial cancer (EEC) and endometrial atypical hyperplasia (EAH). METHODS: This is a single-center retrospective study. A total of 135 patients with EEC and EAH receiving fertility-preserving treatment and...
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