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Article

Schmidtea mediterranea as a Model Organism to Study the Molecular Background of Human Motile Ciliopathies.

International journal of molecular sciences - 24 Feb 2023

Rabiasz Alicja, Ziętkiewicz Ewa

Abstract excerpt

Cilia and flagella are evolutionarily conserved organelles that form protrusions on the surface of many growth-arrested or differentiated eukaryotic cells. Due to the structural and functional differences, cilia can be roughly classified as motile and non-motile (primary). Genetically determined dysfunction of motile cilia is the basis of primary ciliary dyskinesia (PCD), a heterogeneous ciliopathy affecting...

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PMID: 36901899
DOI: 10.3390/ijms24054472
PMCID: PMC10002865

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