Article
Aquatic models of human ciliary diseases.
Genesis (New York, N.Y. : 2000) - 1 Feb 2021
Corkins Mark E, Krneta-Stankic Vanja, Kloc Malgorzata, Miller Rachel K
Abstract excerpt
Cilia are microtubule-based structures that either transmit information into the cell or move fluid outside of the cell. There are many human diseases that arise from malfunctioning cilia. Although mammalian models provide vital insights into the underlying pathology of these diseases, aquatic organisms such as Xenopus and zebrafish provide valuable tools to help screen and dissect out the underlying causes of...
Topics
- Animals
- Ciliopathies
- Disease Models, Animal
- Phenotype
- Xenopus laevis
- Zebrafish