Integrating Network Pharmacology and Bioinformatics to Explore the Effects of Dangshen (Codonopsis pilosula) Against Hepatocellular Carcinoma: Validation Based on the Active Compound Luteolin

Abstract excerpt

Purpose: This study aimed to explore the pharmacological mechanism of Dangshen ( Codonopsis pilosula ) against hepatocellular carcinoma (HCC) based on network pharmacology and bioinformatics, and to verify the anticancer effect of luteolin, the active ingredient of Codonopsis pilosula , on HCC cells. Methods: The effective compounds and potential targets of Codonopsis pilosula were established using the...

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