Article
Individualised stimlation parameters in deep brain stimulation for Parkinson's disease based on disease phenotype and brain connectivity: protocol for a randomised feasibility study in a tertiary care centre (iDBS trial).
BMJ open - 13 Apr 2026
de Ronde Eva M, Birnie Esmee, Rijpma Anne, Arnts Hisse, Bartels Ronald H M A, Esselink Rianne, Vinke R Saman
Abstract excerpt
BACKGROUND: Bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a well-accepted treatment for advanced Parkinson's disease (PD). Currently, programming of the DBS is done in a trial-and-error manner and it can take up to 12 months to reach optimal stimulation parameters. Technological advances in electrode design and implantable pulse generator capabilities lead to an almost infinite number...
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