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Article

Mesonephric-like adenocarcinoma of the ovary with squamoid morular metaplasia, aberrant β-catenin expression, and concurrent FGFR2 and CTNNB1 mutations: a case report.

Virchows Archiv : an international journal of pathology - 1 Jan 2024

Xu Jin, Park Kay J, Rehrauer William M, Weisman Paul S

Abstract excerpt

In general, endometrioid-defining features such as squamoid morular metaplasia are not thought to be associated with mesonephric adenocarcinoma (MA) and mesonephric-like adenocarcinoma (MLA). Here, we report a case of FGFR2-mutated ovarian MLA with squamoid morular metaplasia accompanied by aberrant nuclear and cytoplasmic β-catenin expression and CTNNB1 mutation. Histologically, the tumor showed classical MLA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36856760
DOI: 10.1007/s00428-023-03522-9
PMCID: PMC11826962

Genes

CTNNB1
FGFR2
GATA3
PAX8

Provenance

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