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Article

Cuproptosis-related genes score: A predictor for hepatocellular carcinoma prognosis, immunotherapy efficacy, and metabolic reprogramming

9 Feb 2023

Abstract excerpt

Background Cuproptosis is a newly identified type of programmed cell death, characterized by aggregation of mitochondrial lipoylated proteins and the destabilization of Fe–S cluster proteins triggered by copper. However, its role in hepatocellular carcinoma (HCC) remains unclear. Methods We analyzed the expression and prognostic significance of cuproptosis-related genes using the data obtained from TCGA and ICGC...

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PMID: 36845733
DOI: 10.3389/fonc.2023.1096351

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