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Identification and validation of hub genes and potential drugs involved in osteoarthritis through bioinformatics analysis

9 Feb 2023

Abstract excerpt

Purpose: Osteoarthritis (OA) is a common degenerative disease, which still lacks specific therapeutic drugs. Synovitis is one of the most important pathological process in OA. Therefore, we aim to identify and analyze the hub genes and their related networks of OA synovium with bioinformatics tools to provide theoretical basis for potential drugs. Materials and methods: Two datasets were obtained from GEO. DEGs...

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PMID: 36845391
DOI: 10.3389/fgene.2023.1117713

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