Article
Assessing the relationship between the in silico predicted consequences of 97 missense mutations mapping to 68 genes related to lipid metabolism and their association with porcine fatness traits.
Genomics - 1 Mar 2023
González-Prendes Rayner, Derks Martijn F L, Groenen Martien A M, Quintanilla Raquel, Amills Marcel
Abstract excerpt
In general, the relationship between the predicted functional consequences of missense mutations mapping to genes known to be involved in human diseases and the severity of disease manifestations is weak. In this study, we tested in pigs whether missense single nucleotide polymorphisms (SNPs), predicted to have consequences on the function of genes related to lipid metabolism are associated with lipid phenotypes....
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