Article
Identification of a missense variant in the porcine AGPAT gene family associated with intramuscular fat content through whole-genome sequencing.
Animal genetics - 1 Dec 2022
Molinero Eduard, Pena Ramona N, Estany Joan, Ros-Freixedes Roger
Abstract excerpt
The 1-acylglycerol-3-phosphate O-acyltransferases (AGPATs) are enzymes that catalyze the conversion of lysophosphatidic acid to phosphatidic acid, which is a precursor of triacylglycerol, the main fat reservoir in mammals. We used whole-genome sequencing of 205 pigs to identify 6639 genetic variants in the porcine AGPAT gene family. Of these, 166 common variants in the AGPAT5 gene had significant associations...
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