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Modeling of ACTN4-Based Podocytopathy Using Drosophila Nephrocytes

31 Oct 2022

Abstract excerpt

Introduction Genetic disorders are among the most prevalent causes leading to progressive glomerular disease and, ultimately, end-stage renal disease (ESRD) in children and adolescents. Identification of underlying genetic causes is indispensable for targeted treatment strategies and counseling of affected patients and their families. Methods Here, we report on a boy who presented at 4 years of age with...

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PMID: 36815115
DOI: 10.1016/j.ekir.2022.10.024

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