Article
Mutation pattern of cancer suppressor p53 gene in factory workers exposed to polypropylene and impact on their reproductive hormones.
The journal of gene medicine - 1 Jun 2023
Razak Suhail, Asharf Naeem Mahmood, Abbas Hira, Shaheen Ghazala, Ahmad Waqar, Afsar Tayyaba, Almajwal Ali, Shabbir Maria, Shafique Huma, Jahan Sarwat
Abstract excerpt
BACKGROUND: Polypropylene is a thermoplastic polymer playing the role of an endocrine disruptor that interferes with the union, emission, transport or elimination of normal hormones. Epidemiological information indicated the relation of endocrine-disturbing chemicals with prostate cancer, testis tumor and diminished fertility. p53 is a key tumor silencer gene. The present study aimed to evaluate luteinizing...
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