Article
Detection of single nucleotide polymorphism in HTR4 and its relationship with growth traits in sheep.
Animal biotechnology - 1 Dec 2023
Xu Dan, Wang Xiaojuan, Wang Weimin, Zhang Deyin, Li Xiaolong, Zhang Yukun, Zhao Yuan, Cheng Jiangbo, Zhao Liming, Wang Jianghui, Lin Changchun, Yang Xiaobin, Weng Xiuxiu, Zhang Xiaoxue, Zheng Wenxin
Abstract excerpt
In this study, a single nucleotide polymorphism of HTR4 (hydroxytryptamine receptor 4) was detected using DNA sequencing and KASPar (Kompetitive Allele-Specific PCR) technique with the aim of analyzing its effect on growth traits in 1102 sheep. A synonymous mutation g.101220 C > T located on the fifth intron of the ovis HTR4 gene was detected, and association analysis showed that this mutation was significantly...
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