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Article

Use of Whole-Genome Sequencing of Adenovirus in Immunocompromised Pediatric Patients to Identify Nosocomial Transmission and Mixed-Genotype Infection.

The Journal of infectious diseases - 8 Sept 2018

Houldcroft Charlotte J, Roy Sunando, Morfopoulou Sofia, Margetts Ben K, Depledge Daniel P, Cudini Juliana, Shah Divya, Brown Julianne R, Romero Erika Yara, Williams Rachel, Cloutman-Green Elaine, Rao Kanchan, Standing Joseph F, Hartley John C, Breuer Judith

Abstract excerpt

Background: Adenoviruses are significant pathogens for the immunocompromised, arising from primary infection or reinfection. Serotyping is insufficient to support nosocomial transmission investigations. We investigate whether whole-genome sequencing (WGS) provides clinically relevant information on transmission among patients in a pediatric tertiary hospital. Methods: We developed a target-enriched adenovirus WGS...

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Identifiers

PMID: 29917114
DOI: 10.1093/infdis/jiy323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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