Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a novel pathway in sporadic Amyotrophic Lateral Sclerosis mediated by the long non-coding RNA ZEB1-AS1

2 Feb 2023

Abstract excerpt

BACKGROUND: Deregulation of transcription in the pathogenesis of sporadic Amyotrophic Lateral Sclerosis (sALS) is taking central stage with RNA-sequencing analyses from sALS patients tissues highlighting numerous deregulated long non-coding RNAs (lncRNAs). The oncogenic lncRNA ZEB1-AS1 is strongly downregulated in peripheral blood mononuclear cells of sALS patients. In addition, in cancer-derived cell lines,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Cancer-related molecular mechanisms research
Share to Systemic Sclerosis and Related Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36736597
DOI: 10.1016/j.nbd.2023.106030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a novel pathway in sporadic Amyotrophic Lateral Sclerosis mediated by the long non-coding RNA ZEB1-AS1PMID 36736597Read ↗

The role of long noncoding RNAs in amyotrophic lateral sclerosisSemantic proximity Read ↗

The Expression Discrepancy And Characteristics of Long Non-Coding RNAs In Peripheral Blood Leukocytes From Amyotrophic Lateral Sclerosis PatientsSemantic proximity Read ↗

LncRNAs Associated with Neuronal Development and Oncogenesis Are Deregulated in SOD1-G93A Murine Model of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Investigation Genomic Landscapes, Molecular Mechanisms, and Extracellular Vesicles MiRNAs in Astrocyte and Oligodendrocyte Derived Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral SclerosisSemantic proximity Read ↗

The First Insight into the Hereditary Fusion Gene Landscape of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genesSemantic proximity Read ↗

MicroRNAs in amyotrophic lateral sclerosis: from pathogenetic involvement to diagnostic biomarker and therapeutic agent developmentSemantic proximity Read ↗

Neuregulin-1 and ALS19 (ERBB4): at the crossroads of amyotrophic lateral sclerosis and cancerSemantic proximity Read ↗

Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor NeuronsSemantic proximity Read ↗

The potential of LINGO-1 as a therapeutic target for essential tremor.Semantic proximity Read ↗

A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.