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Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin

1 Jan 2023

Abstract excerpt

Palmoplantar skin is structurally and functionally unique, but the transcriptional programs driving this specialization are unclear. Here, we use bulk and single-cell RNA sequencing of human palm, sole, and hip skin to describe the distinguishing characteristics of palmoplantar and non-palmoplantar skin while also uncovering differences between palmar and plantar sites. Our approach reveals an altered immune...

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PMID: 36732947
DOI: 10.1016/j.celrep.2023.111994

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