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Article

Genetic associations in CHAT and COL11A1 with primary angle-closure glaucoma susceptibility: A systematic review and meta-analysis.

Indian journal of ophthalmology - 1 Feb 2023

Wang Shaowen, Zhang Guowei, Lu Hong

Abstract excerpt

Genome-wide association studies (GWAS) have identified that single-nucleotide polymorphisms (SNPs) rs1258267 in CHAT and rs3753841 in COL11A1 are associated with primary angle-closure glaucoma (PACG). The purpose of the study was to evaluate the association of CHAT rs1258267 and COL11A1 rs3753841 with PACG. A comprehensive electronic database search was performed to include eligible studies, published from...

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Choline O-Acetyltransferase
Collagen Type XI
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Glaucoma, Angle-Closure
Polymorphism, Single Nucleotide

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Identifiers

PMID: 36727317
DOI: 10.4103/ijo.IJO_1226_22
PMCID: PMC10228949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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