Article
Toxoplasma gondii SAG2, SAG3 and GRA6 alleles and single nucleotide polymorphism in congenital infections with known parasite load and clinical outcome.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2023
Targa Lília Spaleta, Santos Emilly Henrique Dos, Yamamoto Lidia, Barreira Gabriel Acca, Rodrigues Karen Alessandra, Rocha Mussya Cisotto, Kanunfre Kelly Aparecida, Okay Thelma Suely
Abstract excerpt
Amniotic fluid DNA samples were genotyped by multilocus-nested-PCR-RFLP, but only three of 11 markers amplified 113 of 122 (92.6%) samples, resulting in 12 untyped and 101 partial non-archetypal genotypes. The 101 typed samples were subdivided into four groups: G1 with 73 samples (5'and 3' SAG2 allele I + SAG3 allele III + GRA6 allele III), 53 had parasite load ≤ 102 parasites/mL (43 asymptomatic, 10 mild...
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