Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal Western diet is associated with distinct preclinical pediatric NAFLD phenotypes in juvenile nonhuman primate offspring.

Hepatology communications - 1 Feb 2023

Nash Michael J, Dobrinskikh Evgenia, Janssen Rachel C, Lovell Mark A, Schady Deborah A, Levek Claire, Jones Kenneth L, D'Alessandro Angelo, Kievit Paul, Aagaard Kjersti M, McCurdy Carrie E, Gannon Maureen, Friedman Jacob E, Wesolowski Stephanie R

Abstract excerpt

Pediatric NAFLD has distinct and variable pathology, yet causation remains unclear. We have shown that maternal Western-style diet (mWSD) compared with maternal chow diet (CD) consumption in nonhuman primates produces hepatic injury and steatosis in fetal offspring. Here, we define the role of mWSD and postweaning Western-style diet (pwWSD) exposures on molecular mechanisms linked to NAFLD development in a cohort...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidants
Share to Diet, Metabolism, and Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet, Western

Share to Fibrosis

Share to Liver Disease Diagnosis and Treatment

Share to Non-alcoholic Fatty Liver Disease

Share to Phenotype

Share to Primates

Source

Open in PubMed Open full text

Identifiers

PMID: 36691970
DOI: 10.1097/HC9.0000000000000014
PMCID: PMC9851700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal Western diet is associated with distinct preclinical pediatric NAFLD phenotypes in juvenile nonhuman primate offspring.PMID 36691970Read ↗

Maternal Western-style Diet Promotes Immune Tolerance and Liver Sinusoidal Endothelial Cell Dysfunction in Nonhuman Primate Juvenile Offspring LiverSemantic proximity Read ↗

Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspringSemantic proximity Read ↗

Developmental Programming of NAFLD by Parental ObesitySemantic proximity Read ↗

Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLDSemantic proximity Read ↗

Developmental origins of nonalcoholic fatty liver disease.Semantic proximity Read ↗

MASLD In Children - A Distinct Phenotype?Semantic proximity Read ↗

Maternal western diet primes non‐alcoholic fatty liver disease in adult mouse offspringSemantic proximity Read ↗

Maternal Western-style diet programs skeletal muscle gene expression in lean adolescent Japanese macaque offspringSemantic proximity Read ↗

Assessment of Fatty Liver in Models of Disease Programming.Semantic proximity Read ↗

Comparison of the Phenotype and Approach to Pediatric vs Adult Patients With Nonalcoholic Fatty Liver Disease.Semantic proximity Read ↗

Early-Life Nutritional Determinants of Pediatric MASLDSemantic proximity Read ↗

A critical appraisal of advances in pediatric nonalcoholic Fatty liver disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.