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Article

HLA-A*01:01 allele diminishing in COVID-19 patients population associated with non-structural epitope abundance in CD8+ T-cell repertoire.

PeerJ - 1 Jan 2023

Shkurnikov Maxim, Nersisyan Stepan, Averinskaya Darya, Chekova Milena, Polyakov Fedor, Titov Aleksei, Doroshenko Dmitriy, Vechorko Valery, Tonevitsky Alexander

Abstract excerpt

In mid-2021, the SARS-CoV-2 Delta variant caused the third wave of the COVID-19 pandemic in several countries worldwide. The pivotal studies were aimed at studying changes in the efficiency of neutralizing antibodies to the spike protein. However, much less attention was paid to the T-cell response and the presentation of virus peptides by MHC-I molecules. In this study, we compared the features of the HLA-I...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epitopes, T-Lymphocyte

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Source

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Identifiers

PMID: 36691482
DOI: 10.7717/peerj.14707
PMCID: PMC9864130

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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