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Article

Effect of calcium ionophore (A23187) on embryo development and its safety in PGT cycles

4 Jan 2023

Abstract excerpt

Background Intracytoplasmic sperm injection (ICSI) has tremendous advantages for resolving the problem of male infertility. However, ICSI fertilization can fail in some patients because of various reasons, primarily because of the failure of oocyte activation. Oocytes have been activated using calcium ionophore (A23187) in previous clinical cases of ICSI fertilization failure. However, studies on the efficiency...

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PMID: 36686427
DOI: 10.3389/fendo.2022.979248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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