Article
The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen.
Scientific reports - 12 Jan 2023
Clochard Gwen-Jirō, Mbengue Aby, Mettling Clément, Diouf Birane, Faurie Charlotte, Sene Omar, Chancerel Emilie, Guichoux Erwan, Hollard Guillaume, Raymond Michel, Willinger Marc
Abstract excerpt
It has been shown that living in risky environments, as well as having a risky occupation, can moderate risk-tolerance. Despite the involvement of dopamine in the expectation of reward described by neurobiologists, a GWAS study was not able to demonstrate a genetic contribution of genes involved in the dopaminergic pathway in risk attitudes and gene candidate studies gave contrasting results. We test the...
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