Article
GWAS Explorer: an open-source tool to explore, visualize, and access GWAS summary statistics in the PLCO Atlas.
Scientific data - 12 Jan 2023
Machiela Mitchell J, Huang Wen-Yi, Wong Wendy, Berndt Sonja I, Sampson Joshua, De Almeida Jonas, Abubakar Mustapha, Hislop Jada, Chen Kai-Ling, Dagnall Casey, Diaz-Mayoral Norma, Ferrell Mary, Furr Michael, Gonzalez Alex, Hicks Belynda, Hubbard Aubrey K, Hutchinson Amy, Jiang Kevin, Jones Kristine, Liu Jia, Loftfield Erikka, Loukissas Jennifer, Mabie Jerome, Merkle Shannon, Miller Eric, Minasian Lori M, Nordgren Ellen, Park Brian, Pinsky Paul, Riley Thomas, Sandoval Lorena, Saxena Neeraj, Vogt Aurelie, Wang Jiahui, Williams Craig, Wright Patrick, Yeager Meredith, Zhu Bin, Zhu Claire, Chanock Stephen J, Garcia-Closas Montserrat, Freedman Neal D
Abstract excerpt
The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial is a prospective cohort study of nearly 155,000 U.S. volunteers aged 55-74 at enrollment in 1993-2001. We developed the PLCO Atlas Project, a large resource for multi-trait genome-wide association studies (GWAS), by genotyping participants with available DNA and genomic consent. Genotyping on high-density arrays and imputation was performed,...
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