Article
A novel active transposon creates allelic variation through altered translation rate to influence protein abundance.
Nucleic acids research - 25 Jan 2023
Chen Guo, Wang Ruilin, Jiang Yizhe, Dong Xiaoxiao, Xu Jing, Xu Qiang, Kan Qiuxin, Luo Zhixiang, Springer Nathan M, Li Qing
Abstract excerpt
Protein translation is tightly and precisely controlled by multiple mechanisms including upstream open reading frames (uORFs), but the origins of uORFs and their role in maize are largely unexplored. In this study, an active transposition event was identified during the propagation of maize inbred line B73. The transposon, which was named BTA for 'B73 active transposable element hAT', creates a novel...
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