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Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells

1 Jan 2023

Abstract excerpt

The relationship between neoantigen recognition by T cells and the clinical success of cancer immunotherapy is beyond doubt.1, 2 Personalized neoantigen-based cancer vaccines and neoantigen-specific T-cell therapy represent promising cancer treatments.3 Challenges yet remain to unleash the full potential of mutanome-based cancer immunotherapy. Among them, the identification and validation of clinically-relevant...

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PMID: 36629052
DOI: 10.1002/ctm2.1174

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