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Pathogen-associated gene discovery workflows for novel antivirulence therapeutic development

9 Jan 2023

Abstract excerpt

Novel therapeutics to manage bacterial infections are urgently needed as the impact and prevalence of antimicrobial resistance (AMR) grows. Antivirulence therapeutics are an alternative approach to antibiotics that aim to attenuate virulence rather than target bacterial essential functions, while minimizing microbiota perturbation and the risk of AMR development. Beyond known virulence factors,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36628845
DOI: 10.1016/j.ebiom.2022.104429

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