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Article

Forest and Trees: Exploring Bacterial Virulence with Genome-wide Association Studies and Machine Learning.

Trends in microbiology - 1 Jul 2021

Allen Jonathan P, Snitkin Evan, Pincus Nathan B, Hauser Alan R

Abstract excerpt

The advent of inexpensive and rapid sequencing technologies has allowed bacterial whole-genome sequences to be generated at an unprecedented pace. This wealth of information has revealed an unanticipated degree of strain-to-strain genetic diversity within many bacterial species. Awareness of this genetic heterogeneity has corresponded with a greater appreciation of intraspecies variation in virulence. A number of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33455849
DOI: 10.1016/j.tim.2020.12.002
PMCID: PMC8187264

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