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Article

Genetic variation in the human olfactory receptor OR5AN1 associates with the perception of musks.

Chemical senses - 1 Jan 2023

Sato-Akuhara Narumi, Trimmer Casey, Keller Andreas, Niimura Yoshihito, Shirasu Mika, Mainland Joel D, Touhara Kazushige

Abstract excerpt

Humans have significant individual variations in odor perception, derived from their experience or sometimes from differences in the olfactory receptor (OR) gene repertoire. In several cases, the genetic variation of a single OR affects the perception of its cognate odor ligand. Musks are widely used for fragrance and are known to demonstrate specific anosmia. It, however, remains to be elucidated whether the OR...

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Identifiers

PMID: 36625229
DOI: 10.1093/chemse/bjac037
PMCID: PMC9874024

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