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Article

Microperimetry and Adaptive Optics Imaging Reveal Localized Functional and Structural Changes in Asymptomatic RPGR Mutation Carriers.

Investigative ophthalmology & visual science - 3 Jan 2023

Roshandel Danial, Lamey Tina M, Charng Jason, Heath Jeffery Rachael C, McLaren Terri L, Thompson Jennifer A, De Roach John N, McLenachan Samuel, Mackey David A, Chen Fred K

Abstract excerpt

Purpose: Female carriers of RPGR mutations demonstrate no significant retinal dysfunction or structural change despite a characteristic tapetal-like reflex. In this study, we examined localized changes of pointwise sensitivity (PWS) and cone density (CD) using microperimetry (MP) and adaptive optics (AO) imaging in female carriers of RPGR mutations. Methods: In this cross-sectional case-control study, MP (MAIA,...

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Identifiers

PMID: 36607619
DOI: 10.1167/iovs.64.1.3
PMCID: PMC9836009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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