Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High throughput sequencing revealed enhanced cell cycle signaling in SLE patients

4 Jan 2023

Abstract excerpt

The multi-system involvement and high heterogeneity of systemic lupus erythematosus (SLE) pose great challenges to its diagnosis and treatment. The purpose of the current study is to identify genes and pathways involved in the pathogenesis of SLE. High throughput sequencing was performed on the PBMCs from SLE patients. We conducted differential gene analysis, gene ontology (GO) analysis, kyoto encyclopedia of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to RNA Research and Splicing
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36599883
DOI: 10.1038/s41598-022-27310-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High throughput sequencing revealed enhanced cell cycle signaling in SLE patientsPMID 36599883Read ↗

ZBP1 is a significant pyroptosis regulator for systemic lupus erythematosusSemantic proximity Read ↗

Transcriptome sequencing reveals novel molecular features of SLE severitySemantic proximity Read ↗

Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients – A Bioinformatics ApproachSemantic proximity Read ↗

Novel potential lncRNA biomarker in B cells indicates essential pathogenic pathway activation in patients with SLESemantic proximity Read ↗

Identification of key interferon-stimulated genes for indicating the condition of patients with systemic lupus erythematosusSemantic proximity Read ↗

Immune cell and TCR/BCR repertoire profiling in systemic lupus erythematosus patients by single-cell sequencingSemantic proximity Read ↗

Identification of monocyte-associated biomarkers in systemic lupus erythematosus and their pan-cancer analysisSemantic proximity Read ↗

Virome analysis provides new insights into the pathogenesis mechanism and treatment of SLE diseaseSemantic proximity Read ↗

Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosusSemantic proximity Read ↗

Identification of mitochondrial function and programmed cell death associated key biomarkers and the circRNA-miRNA-mRNA regulatory network in systemic lupus erythematosusSemantic proximity Read ↗

Full high-throughput sequencing analysis of differences in expression profiles of long noncoding RNAs and their mechanisms of action in systemic lupus erythematosusSemantic proximity Read ↗

Single Cell and Transcriptomic Analysis of Regulatory Mechanisms of Key Genes in Systemic Lupus ErythematosusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.