Article
PI3K polymorphism in patients with sporadic Parkinson's disease.
Medicine - 23 Dec 2022
Su Jiali, Deng Yidong, Cai Benchi, Teng Si, Zhang Shan, Liu Yanhui, Lin Jie, Yang Qiang, Zeng Danting, Zhao Xiuying, Chen Tao
Abstract excerpt
Parkinson's disease (PD) is a common irreversible neurodegenerative disease associated with cognitive impairment. To investigate the serum level of phosphatidylinositol-3-kinase (PI3K) and the distribution of the genotypes and alleles of 3 PI3K single-nucleotide polymorphisms (RS37,30,087, RS37,30,088, and RS37,30,089) in PD patients with different clinical characteristics. A total of 54 PD patients and 50...
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