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Leonurine Suppresses Prostate Cancer Growth in vitro and in vivo by Regulating miR-18a-5p/SLC40A1 Axis

1 Nov 2022

Abstract excerpt

Prostate cancer is a leading cause of cancer-associated death in males. Leonurine (Leo) is a pleiotropic anti-tumor agent isolated from traditional Chinese herb that was used in gynecologic treatments. However, its pharmacological effect against prostate cancer progression remains unclear. Here, we showed that Leo dose dependently inhibited prostate cancer cell proliferation, promoted cell apoptosis, and induced...

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PMID: 36588358
DOI: 10.4103/0304-4920.365459

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