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Article

High-risk genotypes for type 1 diabetes are associated with the imbalance of gut microbiome and serum metabolites.

Frontiers in immunology - 1 Jan 2022

Yue Tong, Tan Huiling, Wang Chaofan, Liu Ziyu, Yang Daizhi, Ding Yu, Xu Wen, Yan Jinhua, Zheng Xueying, Weng Jianping, Luo Sihui

Abstract excerpt

Background: The profile of gut microbiota, serum metabolites, and lipids of type 1 diabetes (T1D) patients with different human leukocyte antigen (HLA) genotypes remains unknown. We aimed to explore gut microbiota, serum metabolites, and lipids signatures in individuals with T1D typed by HLA genotypes. Methods: We did a cross-sectional study that included 73 T1D adult patients. Patients were categorized into two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36582242
DOI: 10.3389/fimmu.2022.1033393
PMCID: PMC9794034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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