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Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants

14 Dec 2022

Abstract excerpt

The BQ and XBB subvariants of SARS-CoV-2 Omicron are now rapidly expanding, possibly due to altered antibody evasion properties deriving from their additional spike mutations. Here, we report that neutralization of BQ.1, BQ.1.1, XBB, and XBB.1 by sera from vaccinees and infected persons was markedly impaired, including sera from individuals boosted with a WA1/BA.5 bivalent mRNA vaccine. Titers against BQ and XBB...

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PMID: 36580913
DOI: 10.1016/j.cell.2022.12.018

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