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Natural phytochemicals prevent side effects in BRCA-mutated ovarian cancer and PARP inhibitor treatment

7 Dec 2022

Abstract excerpt

Ovarian cancer is among the most common malignant tumors in gynecology and is characterized by insidious onset, poor differentiation, high malignancy, and a high recurrence rate. Numerous studies have shown that poly ADP-ribose polymerase (PARP) inhibitors can improve progression-free survival (PFS) in patients with BRCA-mutated ovarian cancer. With the widespread use of BRCA mutation and PARP inhibitor (PARPi)...

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PMID: 36569329
DOI: 10.3389/fphar.2022.1078303

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