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Article

Identifying high-risk phenotypes and associated harms of delayed time-to-antibiotics in patients with ICU onset sepsis: A retrospective cohort study.

Journal of critical care - 1 Apr 2023

Hu Wenhan, Chen Hui, Wang Haofei, Peng Qingyun, Wang Jinlong, Huang Wei, Liu Airan, Xu Jingyuan, Li Qing, Pan Chun, Xie Jianfeng, Huang Yingzi

Abstract excerpt

PURPOSE: To identify phenotypes of Intensive Care Unit (ICU) onset sepsis and its associated harms of delayed time-to-antibiotics. MATERIALS AND METHODS: The Medical Information Mart for Intensive Care IV (MIMIC-IV) database was employed to identify patients with ICU onset sepsis. The primary exposure was time-to-antibiotics, as measured from sepsis recognition to first antibiotic administered. Latent profile...

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PMID: 36565649
DOI: 10.1016/j.jcrc.2022.154221

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