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Article

Identifying High-Risk Subphenotypes and Associated Harms From Delayed Antibiotic Orders and Delivery.

Critical care medicine - 1 Oct 2021

Han Xuan, Spicer Alexandra, Carey Kyle A, Gilbert Emily R, Laiteerapong Neda, Shah Nirav S, Winslow Christopher, Afshar Majid, Kashiouris Markos G, Churpek Matthew M

Abstract excerpt

OBJECTIVES: Early antibiotic administration is a central component of sepsis guidelines, and delays may increase mortality. However, prior studies have examined the delay to first antibiotic administration as a single time period even though it contains two distinct processes: antibiotic ordering and antibiotic delivery, which can each be targeted for improvement through different interventions. The objective of...

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Identifiers

PMID: 33938715
DOI: 10.1097/CCM.0000000000005054
PMCID: PMC8448901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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