Article
Impact of elexacaftor/tezacaftor/ivacaftor on depression and anxiety in cystic fibrosis.
Therapeutic advances in respiratory disease - 1 Jan 2000
Zhang Lijia, Albon Dana, Jones Marieke, Bruschwein Heather
Abstract excerpt
BACKGROUND: Cystic fibrosis (CF) is associated with worsening of depression and anxiety symptoms. Elexacaftor/tezacaftor/ivacaftor (Trikafta®), a cystic fibrosis transmembrane regulator (CFTR) modulator approved in 2019, significantly improves lung function, decreases pulmonary exacerbations, and improves quality of life. Studies are needed to evaluate the effects of Trikafta on symptoms of anxiety and...
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